Myelin Damage Innovations
MS is a chronic disease that affects approximately 2.3 million people worldwide. In MS, the sheath covering the nerve fibers of the brain and spinal cord is damaged, slowing or preventing electrical signals from reaching the eyes, muscles and other parts of the body. This sheath is called myelin. Although myelin can grow back through exposure to thyroid hormones, researchers did not continue thyroid hormone therapy due to unacceptable side effects. Although there are many treatments and medications that reduce symptoms of MS, there is no cure. "Myelinate demyelinated axons and nerve fibers, and ours does," "It could have a significant impact on patients weakened by MS," said Bourdette. The discovery, if ultimately proven in clinical trials involving people, seems to achieve two important goals:
Repairing myelin with minimal side effects: The study showed that the compound - known as sobetiroma - promotes remylenation without the serious side effects of thyroid hormone therapy. Thyroid hormone therapy has not been tried in people because high chronic exposure known as hyperthyroidism damages the heart, bones and skeletal muscles.
Effective childbirth: researchers have developed a new derivative of sobetiroma (Sob-AM2) which penetrates the blood-brain barrier, thereby increasing the infiltration of the central nervous system
High Impact List of Articles
-
The Secret Lives of Human Herpes Virus 6 (HHV-6)
Benjamin M Blumberg Commentary: Neurological Disorders
-
The Secret Lives of Human Herpes Virus 6 (HHV-6)
Benjamin M Blumberg Commentary: Neurological Disorders
-
Resting State Functional Connectivity and Thrombolysis Mediated Reperfusion in Acute Ischemic Stroke: A Pilot Study
Priyantha Herath, Taylor Hanayik, Kaitlin Krebs, Lauren Dennis, Christopher Rorden, Julius Fridriksson and Souvik Sen Research Article: Neurological Disorders
-
Resting State Functional Connectivity and Thrombolysis Mediated Reperfusion in Acute Ischemic Stroke: A Pilot Study
Priyantha Herath, Taylor Hanayik, Kaitlin Krebs, Lauren Dennis, Christopher Rorden, Julius Fridriksson and Souvik Sen Research Article: Neurological Disorders
-
Risk Factors for Psychiatric Complications after Deep Brain Stimulation in Patients with Parkinson’s Disease: An Observational Study
Akihiro Shiina, Tatsuya Yamamoto, Yoshinori Higuchi, Yoshitaka Yamanaka, Shigeki Hirano, Masato Asahina and Masaomi Iyo Research Article: Neurological Disorders
-
Risk Factors for Psychiatric Complications after Deep Brain Stimulation in Patients with Parkinson’s Disease: An Observational Study
Akihiro Shiina, Tatsuya Yamamoto, Yoshinori Higuchi, Yoshitaka Yamanaka, Shigeki Hirano, Masato Asahina and Masaomi Iyo Research Article: Neurological Disorders
-
Carcinoma Lung Presenting as Intracranial Hypertension and Lower Cranial Nerve Palsies
Chakor Rahul T and Eklare Nishikant C Case Report: Neurological Disorders
-
Carcinoma Lung Presenting as Intracranial Hypertension and Lower Cranial Nerve Palsies
Chakor Rahul T and Eklare Nishikant C Case Report: Neurological Disorders
-
Investigation of an Optimized Protocol for Brucine-Induced Seizure Model
Xinxin Fan, Tinglei Li, Jinmei Li, Yingying Li and Dan Chen Research Article: Neurological Disorders
-
Investigation of an Optimized Protocol for Brucine-Induced Seizure Model
Xinxin Fan, Tinglei Li, Jinmei Li, Yingying Li and Dan Chen Research Article: Neurological Disorders
Conference Proceedings
-
Structural and functional MRI correlates of poststroke depression
Wai Kwong Tang Keynote: Neurological Disorders
-
Structural and functional MRI correlates of poststroke depression
Wai Kwong Tang Keynote: Neurological Disorders
-
Resist the urge: Exploring the sources of abstinence self-efficacy of drug rehabilitation residents in Iloilo
Marycon Anne C Boston Ba Posters & Accepted Abstracts: Neurological Disorders
-
Resist the urge: Exploring the sources of abstinence self-efficacy of drug rehabilitation residents in Iloilo
Marycon Anne C Boston Ba Posters & Accepted Abstracts: Neurological Disorders
-
New Opportunities in Pediatric Epilepsy Surgery
Elaine Wyllie Scientific Tracks Abstracts: Neurological Disorders
-
New Opportunities in Pediatric Epilepsy Surgery
Elaine Wyllie Scientific Tracks Abstracts: Neurological Disorders
-
Novel lignan derivatives from the twigs of Cinnamomum cassia and their potential neuroprotective effects
Jing Fu, Guo Yuan Zhu, Zhi Hong Jiang, Xin Liu, Ji Yang and Xiao Jun Yao Posters & Accepted Abstracts: Neurological Disorders
-
Novel lignan derivatives from the twigs of Cinnamomum cassia and their potential neuroprotective effects
Jing Fu, Guo Yuan Zhu, Zhi Hong Jiang, Xin Liu, Ji Yang and Xiao Jun Yao Posters & Accepted Abstracts: Neurological Disorders
-
Cannabinoids and endocannabinoids as potential therapeutic drugs for multiple sclerosis
Panagiotis Zogopoulos, Ioannis Ydraios, Aggelos Leventis, Panagiotis Kokkalis and Georgios Tsanis Posters-Accepted Abstracts: Neurological Disorders
-
Cannabinoids and endocannabinoids as potential therapeutic drugs for multiple sclerosis
Panagiotis Zogopoulos, Ioannis Ydraios, Aggelos Leventis, Panagiotis Kokkalis and Georgios Tsanis Posters-Accepted Abstracts: Neurological Disorders
Relevant Topics in Neuroscience & Psychology
Spanish 
Chinese 
Russian 
German 
French 
Japanese 
Portuguese 
Hindi 