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Journal of Clinical Neurology and Neurosurgery

Journal of Clinical Neurology and Neurosurgery

ISSN: 2684-6012

Open Access
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Hair Follicle Stem Cells Open Access Journals

Hair follicles buildup themselves though the hair cycle, suggesting the presence of intrinsic stem cells. stem cells lie in the bulbar region of hair follicles, They were detected in the bulge area, a contiguous part of outer root sheath, that provides the insertion point for small muscle that are attached to hair follicle and marks the bottom  portion. The bulge cells are structurally undifferentiated and slow-cycling under the normal conditions. The bulge cells possess  multipotency to regenerate not only hair follicles but also sebaceous glands and epidermis. Mainly, novel cell surface markers were identified on human bulge cells using precise laser capture microdissection and microarray analyses. Use of these markers enabled the successful enrichment of living human bulge cells, raising the possibility of future treatments of hair disorders using stem cells. Quality of bulge cell biology includes the importance of bulge cells as a gene therapy target and their possible roles in formation of tumours. The top open access journals are freely and hopefully available on the public internet domain, allowing any end users to read, download, copy, distribute on  prink and search or link to the full texts of the articles.

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Citations: 2

Journal of Clinical Neurology and Neurosurgery received 2 citations as per Google Scholar report

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