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Haemochromatosis Journals | Open Access Journals

Journal of General Practice

ISSN: 2329-9126

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Haemochromatosis Journals

Hemochromatosis is now known to be an iron storage disease with genetic heterogeneity but with a last common metabolic pathway leading to inappropriate production of the hormone hepcidin. This leads to increased intestinal absorption and the deposition of excessive amounts of iron in the parenchymal cells, which in turn leads to tissue damage and organ failure. A clinical puzzle was the variable clinical expression with some patients with hepatic cirrhosis at a young age and others with almost asymptomatic life. Research is in the process of solving this puzzle by identifying environmental factors - in particular alcohol consumption - and the associated modifier genes that modulate phenotypic expression. A high index of suspicion is required for early diagnosis, but this can lead to presymptomatic treatment and normal life expectancy. Venesection therapy (phlebotomy) remains the mainstay of therapy, but alternative therapies are the subject of current research.

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Conference Proceedings

Breast cancer-targeted delivery of BRCA1 and BRCA2 tumor suppressor genes using carbonate apatite inorganic nanoparticles
Nabilah Ibnat and Md Ezharul Hoque Chowdhury
Posters & Accepted Abstracts: Cancer Science & Therapy
Breast cancer-targeted delivery of BRCA1 and BRCA2 tumor suppressor genes using carbonate apatite inorganic nanoparticles
Nabilah Ibnat and Md Ezharul Hoque Chowdhury
Posters & Accepted Abstracts: Cancer Science & Therapy
Taurin upregulated gene 1 functions as a master regulator to coordinate glycolysis and metastasis in hepatocellular carcinoma
Kwang-Huei Lin and Yang-Hsiang Lin
Posters & Accepted Abstracts: Cancer Science & Therapy
Taurin upregulated gene 1 functions as a master regulator to coordinate glycolysis and metastasis in hepatocellular carcinoma
Kwang-Huei Lin and Yang-Hsiang Lin
Posters & Accepted Abstracts: Cancer Science & Therapy
Role of genetic testing in lung transplantation
Mohamed S A Mohamed
Posters & Accepted Abstracts: Pulmonary & Respiratory Medicine
Role of genetic testing in lung transplantation
Mohamed S A Mohamed
Posters & Accepted Abstracts: Pulmonary & Respiratory Medicine
Coexpression of cytosine deaminase and carboxyl esterase in genetically engineered stem cells migrated ovarian cancer cells and reduced their cell growth through tumor tropic effect
Kyung-a hwang, Min-a park and Kyung-chul choi
Posters & Accepted Abstracts: Cancer Science & Therapy
Coexpression of cytosine deaminase and carboxyl esterase in genetically engineered stem cells migrated ovarian cancer cells and reduced their cell growth through tumor tropic effect
Kyung-a hwang, Min-a park and Kyung-chul choi
Posters & Accepted Abstracts: Cancer Science & Therapy
Evaluation of the SYT-SSX2 fusion gene transcript in synovial sarcoma cells and microvesicles as a potential biomarker for synovial sarcoma
Fricke A, Ullrich P V, Cimniak A F V, Follo M, Nestel S, Heimrich B, Nazarenko I, Stark G B, Bannasch H, Braig D and Eisenhardt S U
Scientific Tracks Abstracts: Cancer Science & Therapy
Evaluation of the SYT-SSX2 fusion gene transcript in synovial sarcoma cells and microvesicles as a potential biomarker for synovial sarcoma
Fricke A, Ullrich P V, Cimniak A F V, Follo M, Nestel S, Heimrich B, Nazarenko I, Stark G B, Bannasch H, Braig D and Eisenhardt S U
Scientific Tracks Abstracts: Cancer Science & Therapy

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Citations: 1047

Journal of General Practice received 1047 citations as per Google Scholar report

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