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Comparitive Genome Hybridization Impact Factor | Open Access Journals
Journal of Genetics and Genomes

Journal of Genetics and Genomes

ISSN: 2684-4567

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Comparitive Genome Hybridization Impact Factor

Comparative genomic hybridization (CGH) could even be a molecular cytogenetic method for analysing copy number variations (CNVs) relative to ploidy level within the DNA of a test sample compared to a reference sample, without the necessity for culturing cells. The aim of this system is to quickly and efficiently compare two genomic DNA samples arising from two sources, which are most frequently closely related, because it's suspected that they contain differences in terms of either gains or losses of either whole chromosomes or subchromosomal regions (a portion of an entire chromosome). This technique was originally developed for the evaluation of the differences between the chromosomal complements of solid tumor and normal tissue,[1] and has an improved resolution of 5–10 megabases compared to the more traditional cytogenetic analysis techniques of giemsa banding and fluorescence in place hybridization (FISH) which are limited by the resolution of the microscope utilized.

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