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Circulating Angiotensin Review Articles | Open Access Journals
Journal of Health Education Research & Development

Journal of Health Education Research & Development

ISSN: 2380-5439

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Circulating Angiotensin Review Articles

To control body fluid volume homeostasis is essential to life and the complex system devoted to this task in humans is the result of an evolutionary process that was shaped by survival responses. To respond to trauma for example, activation of the sympathetic nervous system promotes the release of renin, angiotensin, aldosterone, catecholamine and natriuretic peptide whose effects maintain fluid pressure in the circulation despite volume loss due to haemorrhage. The maintenance of volume homeostasis allowed animals to migrate from the sea's salty water to fresh water and dry lands. In human evolution, the renin–angiotensin system (RAS) played an important role given its ability to control salt intake and stimulate thirst. The study of contemporary primitive tribes advocate that hunting–gathering ancestors survived on little salt possibly thanks to RAS activation without developing hypertension. As eating habits changed, salt intake also increased, turning blood pressure increase mediated by RAS activation into a negative factor. Thus, natural excerpt was strongly influenced by the development of hypertension, whose incidence varied widely among populations with different geographic and ethnic origins

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Journal of Health Education Research & Development received 531 citations as per Google Scholar report

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