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Journal of Surgery

Journal of Surgery

ISSN: [Jurnalul de chirurgie]
ISSN: 1584-9341

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Cachexia-review-articles.php

Cachexia is defined as a state of extreme wasting with marked weight loss, anorexia and lassitude. About half of all cancer patients have cachexia syndrome characterized by loss of adipose tissue and skeletal muscle mass. These patients have a shorter survival time compared to that of patients without weight loss. Abnormal metabolism is believed to be the basis of cachexia status in patients with advanced cancer. Cachexia induces cytokines, in particular tumor necrosis factor (TNF) -α, IL-1 and IL-6, is believed to inhibit the activity of lipoprotein lipase (LPL), and thus induces weight loss due reduction of fat build up in tissues. Therefore, it is believed that wasting of cancer patients could be avoided and cachexia improved by increasing LPL activity. The journal articles are a summary of the current state of knowledge on a particular research topic. They analyze or discuss research previously published by scientists and academics rather than reporting new research results. The journal article is in the form of systematic reviews and literature reviews and constitutes a form of secondary literature. Systematic reviews determine an objective list of criteria and find all previously published original research articles that meet the criteria. They then compare the results presented in these articles. Literature reviews, on the other hand, provide a summary of what the authors believe to be the best and most relevant previous publications. The concept of "review article" is distinct from the concept of peer-reviewed literature. An exam may be peer reviewed, and an exam may not be peer reviewed.

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Citations: 288

Journal of Surgery received 288 citations as per Google Scholar report

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