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Best Top Journals List In Organic Process Research | Open Access Journals

Journal of Pharmacognosy & Natural Products

ISSN: 2472-0992

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Best Top Journals List In Organic Process Research

A range of generic active pharmaceutical ingredients has been examined for patterns and potential chiral alcohol derivatives within their structures that could be used as key synthetic intermediates. For seven generic active pharmaceutical ingredients (API), eight precursor ketones were acquired and then subjected to a reduction of> 400 ketone reductases commercially available from different suppliers. Positive screening results were obtained for five screened ketones, with several ketone reductases available for each successful ketone. Selectivity was generally> 99.5% ee in most cases, including for the opposite enantiomer. The best three examples were then optimized and quickly scaled to the 1 L scale with high conversion and isolated yield while maintaining selectivity> 99.5% ee for the desired chiral alcohol enantiomer . This work illustrates that where a wide range of enzymes is available, enzymes that are productive to give one or the other enantiomer of alcohol can be easily identified for many ketones and quickly scaled up to produce alcohols. chirals. This approach is particularly applicable to the generation of chiral API intermediaries

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Chinese traditional medicine - The fruitful approach to new drug discovery
Aihua Liang
Scientific Tracks Abstracts: Pharmaceutical Regulatory Affairs: Open Access
Chinese traditional medicine - The fruitful approach to new drug discovery
Aihua Liang
Scientific Tracks Abstracts: Pharmaceutical Regulatory Affairs: Open Access
Pharmacogenetic: Regulatory considerations, Cuban guidance
Diadelis Remirez Figueredo
Scientific Tracks Abstracts: Pharmaceutical Regulatory Affairs: Open Access
Pharmacogenetic: Regulatory considerations, Cuban guidance
Diadelis Remirez Figueredo
Scientific Tracks Abstracts: Pharmaceutical Regulatory Affairs: Open Access
Inflectra-our experience on immunogenicity (case series)
Rodica Olteanu, Alexandra Zota and Magda Constantin
Posters & Accepted Abstracts: Journal of Bioanalysis & Biomedicine
Inflectra-our experience on immunogenicity (case series)
Rodica Olteanu, Alexandra Zota and Magda Constantin
Posters & Accepted Abstracts: Journal of Bioanalysis & Biomedicine
Determination of Antioxidant Activity and Identification of Active Compounds From the Ethyl Acetate Extract of Avocado Peel
Irma Antasionasti, Sugeng Riyanto and Abdul Rohman
Scientific Tracks Abstracts: Journal of Pharmacognosy & Natural Products
Determination of Antioxidant Activity and Identification of Active Compounds From the Ethyl Acetate Extract of Avocado Peel
Irma Antasionasti, Sugeng Riyanto and Abdul Rohman
Scientific Tracks Abstracts: Journal of Pharmacognosy & Natural Products
Challenges and approaches in demonstrating biosimilarity at the physicochemical and biological level
Jill A Myers
Scientific Tracks Abstracts: Journal of Bioanalysis & Biomedicine
Challenges and approaches in demonstrating biosimilarity at the physicochemical and biological level
Jill A Myers
Scientific Tracks Abstracts: Journal of Bioanalysis & Biomedicine

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Citations: 606

Journal of Pharmacognosy & Natural Products received 606 citations as per Google Scholar report

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