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Journal of Formulation Science & Bioavailability

ISSN: 2577-0543

Open Access

Articles in press and Articles in process

    Mini Review Pages: 1 - 2

    Formulation Revolution: Advancements in Bioavailability Analysis

    Pauric Bannigan

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    The pharmaceutical industry is witnessing a paradigm shift in drug formulation techniques, driven by the quest for enhancing drug efficacy
    and patient outcomes. One of the critical aspects of this evolution is the focus on bioavailability analysis. Bioavailability, the extent and rate at
    which a drug enters systemic circulation, plays a pivotal role in determining its therapeutic effectiveness. Recent advancements in bioavailability
    analysis methodologies have not only enabled a deeper understanding of drug absorption kinetics but also paved the way for the development
    of more efficient and patient-friendly formulations. This article explores the key innovations in bioavailability analysis and their implications for
    drug formulation revolution. Before delving into advancements, it's crucial to grasp the concept of bioavailability. When a drug is administered, it
    undergoes various processes such as dissolution, absorption, metabolism and excretion. Bioavailability refers to the fraction of the administered
    dose that reaches systemic circulation unchanged and the rate at which it reaches the target site. Factors such as drug formulation, route of
    administration and patient-specific variables influence bioavailability.

    Mini Review Pages: 1 - 2

    Enhancing Drug Delivery: Formulation Techniques and Bioavailability Evaluation

    Suñé Negre

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    The optimization of drug delivery is crucial for improving therapeutic outcomes in pharmaceutical sciences. This article explores formulation
    techniques and bioavailability evaluation methods essential for refining drug delivery systems. Nanoformulations like nanoparticles, liposomes,
    and micelles offer benefits such as increased solubility and targeted delivery. Lipid-based delivery systems, such as nanoemulsions and solid lipid
    nanoparticles, utilize lipids to enhance drug absorption and stability. Controlled release systems, prodrug design, and pharmacokinetic studies
    further optimize drug delivery by modulating release kinetics and improving bioavailability. In vitro-in vivo correlation and advanced imaging
    techniques provide precise evaluation of drug bioavailability and distribution. Integrating formulation science and bioavailability assessment
    promises the development of safer more effective drug delivery systems, advancing pharmaceutical innovation for improved patient care.

    Mini Review Pages: 1 - 2

    Navigating Drug Development: Formulation Engineering and Bioavailability Analysis

    Tony Zhou

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    Drug development is a complex and meticulous process that requires numerous steps to bring a new therapeutic agent from conception to the
    market. Among the pivotal stages is formulation engineering and bioavailability analysis, where the drug is crafted into a viable product with
    optimal efficacy and safety profiles. This article delves into the crucial steps involved in these processes and highlights their significance in
    the pharmaceutical industry. Formulation engineering involves the art and science of designing a drug product that ensures stability, efficacy
    and patient compliance. It begins with selecting appropriate drug candidates and excipients, followed by optimizing the formulation to achieve
    the desired therapeutic outcome. Several factors influence formulation design, including the physicochemical properties of the drug, route of
    administration, and intended dosage form.

    Mini Review Pages: 1 - 2

    Navigating Formulation Challenges: Innovations in Bioavailability Evaluation

    Arno Kwade

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    Formulation challenges are ubiquitous in the pharmaceutical industry, often posing significant hurdles in the development of effective drug delivery
    systems. Among these challenges, optimizing bioavailability stands out as a paramount objective. Bioavailability, the fraction of administered drug
    that reaches systemic circulation, profoundly influences a drug's therapeutic efficacy and clinical outcomes. In this article, we explore the evolving
    landscape of bioavailability evaluation and the innovative strategies revolutionizing drug formulation to overcome these challenges. Bioavailability
    is a multifaceted concept influenced by various factors such as drug solubility, permeability, metabolism, and formulation characteristics. It is a
    critical determinant of a drug's pharmacokinetic profile, influencing its onset of action, duration of effect, and overall therapeutic response. Poor
    bioavailability can lead to suboptimal drug concentrations at the target site, resulting in therapeutic failure or increased risk of adverse effects.

    Short Communication Pages: 1 - 3

    From Lab to Market: Navigating Formulation Strategies and Bioavailability Testing in Pharmaceutical Development

    Yang Tian

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    The journey of a pharmaceutical product from laboratory research to
    market availability involves meticulous formulation design and rigorous
    bioavailability testing. Formulation strategies play a crucial role in optimizing
    drug delivery, while bioavailability testing ensures the effectiveness and safety
    of the final product. This article explores the formulation strategies employed
    in pharmaceutical development and the significance of bioavailability testing
    in transitioning drugs from the lab to the market. Poor solubility is a common
    challenge in drug development, limiting the bioavailability and therapeutic
    efficacy of many compounds. Formulation strategies such as solid dispersion,
    nanoemulsions, and cyclodextrin complexation aim to enhance drug solubility
    by improving dissolution rates and increasing surface area available for
    absorption.

    Brief Report Pages: 1 - 2

    Optimizing Absorption: Strategies in Formulation Design and Bioavailability Assessment

    Hao Yang

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    In the realm of pharmaceutical development, the journey from discovery
    to therapeutic efficacy hinges on the ability of a drug to reach its target site
    in the body at the right concentration and duration. Central to this process is
    absorption, the gateway through which drugs enter systemic circulation and
    exert their pharmacological effects. Formulation design and bioavailability
    assessment play pivotal roles in optimizing absorption, ensuring that drugs
    achieve their intended therapeutic outcomes. This article explores the
    strategies employed in formulation design and bioavailability assessment to
    enhance drug absorption and efficacy. Poor aqueous solubility is a common
    challenge encountered in drug development, leading to limited dissolution
    and reduced absorption.

    Opinion Pages: 1 - 2

    Pharmacokinetic Parameters: Understanding the Dynamics of Drug Absorption, Distribution, Metabolism and Excretion

    Kristy Robson

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    Pharmacokinetic parameters are essential metrics used to characterize
    the disposition of drugs within the body, providing valuable insights into their
    absorption, distribution, metabolism, and excretion processes. Understanding
    pharmacokinetic parameters is crucial for optimizing drug dosing regimens,
    predicting drug interactions, and assessing bioavailability and therapeutic
    efficacy. This article explores the key pharmacokinetic parameters and
    their significance in pharmaceutical development and clinical practice.
    AUC represents the total systemic exposure to a drug over time and is a
    fundamental pharmacokinetic parameter used to assess drug bioavailability
    and overall drug exposure.

    Perspective Pages: 1 - 2

    Unlocking Bioavailability: Strategies for Formulation Optimization

    Engel Manchado

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    Bioavailability plays a pivotal role in the efficacy of pharmaceuticals,
    influencing how effectively a drug is absorbed and utilized by the body.
    Maximizing bioavailability is a crucial objective in drug formulation, as it
    directly impacts therapeutic outcomes. In this article, we explore various
    strategies for optimizing bioavailability through formulation techniques,
    highlighting the importance of innovation and precision in pharmaceutical
    development. Bioavailability, a fundamental concept in pharmacology and
    pharmaceutical sciences, refers to the fraction of an administered drug or
    compound that reaches systemic circulation in its active form, thereby exerting
    pharmacological effects. It plays a crucial role in determining the onset,
    intensity and duration of drug action, ultimately influencing therapeutic efficacy
    and patient outcomes.

    Commentry Pages: 1 - 2

    Unlocking Therapeutic Potential: Strategies for Formulation Design and Bioavailability Assessment

    Kwang Mook

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    The effectiveness of pharmaceutical interventions relies not only on the
    potency of the active ingredients but also on their ability to reach the target
    site within the body in a form that can exert its therapeutic action. Maximizing
    therapeutic impact necessitates a profound understanding of formulation
    design and bioavailability assessment. These aspects are pivotal in ensuring
    optimal drug delivery, efficacy and patient compliance. In this article, we delve
    into the key strategies involved in formulating pharmaceuticals and assessing
    their bioavailability to unlock their full therapeutic potential.

    Short Communication Pages: 1 - 3

    Unveiling the Science behind Bioavailability: Formulation Insights and Analysis Methods

    Daniele Piome

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    In the realm of pharmaceuticals and nutraceuticals, the concept of
    bioavailability stands as a critical determinant of efficacy. Bioavailability
    essentially refers to the proportion of a substance that enters circulation
    when introduced into the body, thus having an active effect. Understanding
    and enhancing bioavailability is paramount for optimizing the therapeutic or
    nutritional benefits of compounds.

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Google Scholar citation report
Citations: 23

Journal of Formulation Science & Bioavailability received 23 citations as per Google Scholar report

Journal of Formulation Science & Bioavailability peer review process verified at publons

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