National Institutes of Health, Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), USA
Wenpei Fan has received his Doctoral degree in Materials Physics and Chemistry. State Key Laboratory of High Performance Ceramics and Superfine Microstructures. He is skilled at the culture of cancerous cells (or other cell lines) and evaluation of cell toxicity, cell death mechanism, cell cycle distribution, intracellular drug release, etc. He is experienced in various synthetic methods and surface coating strategies including hydrothermal method, thermal decomposition method, water-in-oil reverse microemulsion method, mesoporous silica coating method, biological conjugation strategy, etc.
His Research interests focuses on the
Design and synthesis of various multifunctional nanotheranostic systems including superparamagnetic nanoparticles (SPIONs), lanthanide ions doped upconversion nanoparticles (UCNPs), fluorescent quantum dots (QDs), hollow/rattle-structured mesoporous silica nanoparticles, etc.
Development of powerful on-demand multi-modal imaging probes that integrate various diagnostic modalities (e.g., MRI, CT, PET, etc) within a single system.
Fabrication of targeted delivery/stimuli (e.g., PH, temperature, redox, etc) responsive drug release systems and other NIR light/X-ray activated nanotheranostic systems.
Design of novel biomedical materials via smart biological engineering and use of new biological analytic methods for the efficient diagnosis and therapy of various diseases.
Evaluation of long-term in vitro & in vivo nano-biosafety and nano-biological effects of various biomedical materials.