Journal of Computer Science & Systems Biology

Sriram Neelamegham

Sriram Neelamegham
Professor, Department of Chemical and Biological Engineering
State University of New York, USA

Biography

Ph.D Rice University Chemical/Biomedical Engineering 1996B.Tech Indian Institute of Technology  Chemical Engineering 

Research Interest

Research in our laboratory lies in the fields of Biomedical Engineering and Vascular Biology. The underlying theme is to apply novel bioengineering techniques and quantitative methodologies in combination with fundamental biological principles, to elucidate the parameters and mechanisms that regulate leukocyte and platelet function. The importance of the studies stem from the fact that ailments of the blood involving these cell types account for a sizable fraction of inflammatory and thrombotic disorders. The focus of our work is on three families of adhesion molecules and their ligands expressed on blood cells and the vascular endothelium. These molecules are members of the selectin, integrin and Ig gene superfamily. Ongoing projects in the laboratory also examine the effects of fluid shear on the structure and function of plasma protein, von Willebrand Factor