Cancer Science & Therapy

ISSN: 1948-5956

Open Access

Current Issue

Volume 12, Issue 5 (2020)

    Research Article Pages: 1 - 4

    Depression, Anxiety and Quality of Life among Cancer Patients: A Cross-Sectional Study in Saudi Arabia

    Nouf Almutairi, Maryam Alharbi, Baraa M. Hammoudi and Othman Almutairi

    DOI: 10.37421/jcst.2020.12.5-1

    1.1 Introduction: Cancer patients have higher incidence of anxiety and depression which have a negative impact on the quality of their life independently and dependently from cancer. This Study was conducted to assess the relationship of anxiety, depression and quality of life among cancer patients in Saudi Arabia.

    1.2 Methods: This is a cross-sectional study conducted on cancer patients who underwent routine Outpatient health-care services in a tertiary care hospital in Riyadh, Saudi Arabia.

    1.3 Results: In this study 393 cancer patients were included. Majority of them were females, married, aged between 40-60 years old. In 31% of patients had breast cancer and the 2nd most prevalent cancer was lymphoma (7.3%). Majority of patients had neither depression nor anxiety with the following rates respectively [71.1%, 86.1%]. The assessed quality of life components showed the following ; (51%) had a low quality of life, (56.7%) had a low independent lifestyle, (60.5%) low psychological coping, (52%) had high pain occurrence, (64.8%) had a good relationship, (86.1%) good senses and (57%) had good mental health. Anxiety and depression [AD] score was found to be statistically significant in 32.4% of patients in the following components ; Age less than 30 years old, having lymphoma or ovarian cancer, being divorced, having a bachelor degree or no education at all and the need of a caregiver.

    1.4 Conclusion: The prevalence of low QOL (Quality of Life) is high among Saudi Cancer patient and the coexistence of anxiety occurred only in one third of all patients. Anxiety and depression appear to be not contributing to the low quality of life in cancer patients except in certain subgroups in which psychological interventions shall improve the quality of their lives.

    Case Report Pages: 313 - 314

    Clear Cell Carcinoma of the Ovary: A Case Report

    Berrada S, Mahdi L, El Hassani M, Kouach J and Moussaoui D

    DOI: 10.37421/jcst.2020.12.5-2

    Clear cell carcinomas (CCCs) occur most often in young women (median age: 20 years) even before the first pregnancy. It is essential to be conservative and to respect the genital system as much as possible to preserve ovarian hormonal function and fertility. Mutations in KRAS, BRAF, and TP53 are present in some clear cell carcinomas, but their frequency is generally low. Mutations predicted to deregulate PI3K/PTEN signaling. Because of resistance to the usual platinum and taxane chemotherapies, the advanced stages have a much worse prognosis than that of serous tumors. Thus, some studies have suggested that CCCs may be more sensitive to a combination of irinotecan than paclitaxel-based chemotherapy.

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