Center of AIDS Treatment with TCM, China Academy of Chinese Medical Sciences, Nanxiaojie Dongzhimennei Street Number 16, Dongcheng District, Beijing, China
Research Article
The Effects of the Jiangzhi Granule, a Traditional Chinese Medicine, on Dyslipidemia in Patients with HIV Infection Receiving Highly Active Antiretroviral Therapy: A Randomized, Double-Blind, Two-Group Trial
Author(s): Ying L, Xia L, Qiaoli Y, Wen Z, Qingfei X, Fuchun Z, Jianping M, Mingxiang Z, Wenhui L, Jianhua H and Jian W*
Background and Importance: Antiretroviral therapy-associated side effects may lead to an increased risk of dyslipidemia on HIV patients. Exploring an alternative approach to treat antiretroviral therapy (ART)-associated dyslipidemia, especially for those who cannot tolerate statins is important. This study investigated whether the Jiangzhi granule is effective and safe on dyslipidemia in patients with HIV infection receiving highly active antiretroviral therapy.
Methods: Design, setting, and participants- A randomized, double blind, multicenter and placebo-controlled clinical trial of the Jiangzhi granule vs placebo in a factorial design for 24 weeks was conducted in 286 patients infected with HIV with dyslipidemia who were receiving ART at five Class III Grade I hospitals in China between November 2013 to September 2015.
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Journal of AIDS & Clinical Research received 4463 citations as per Google Scholar report
