Neurological Disorders

ISSN: 2329-6895

Open Access

Ulf Kallweit

Department of Medicine, Witten/Herdecke University, Germany

  • Research Article   
    Independency of Selective Neuropsychological Dysfunctions from Subjective Daytime Sleepiness in Drug-Naive Patients with Narcolepsy
    Author(s): Vincent Marcel Eric Lothar Nin*, Ulf Kallweit, Markus Ramm and Martina Piefke

    Besides key symptoms of narcolepsy such as excessive daytime sleepiness, cataplexy, and disturbed nighttime sleep, patients affected by the disease also suffer from cognitive deficits, particularly impairments in attention, concentration, and various memory skills. However, it is still not fully understood to what extent cognitive impairments are independent of daytime sleepiness. In this study we aimed at identifying the taxonomy of neuropsychological dysfunctions in patients with narcolepsy without any stimulant or specific narcolepsy medication and the degree of independency of specific cognitive impairments of subjective daytime sleepiness. We expected that memory impairments, prefrontal dysfunctions, and disturbed emotion processing are independent of subjective daytime sleepiness and age. 22 patients with narcolepsy and 89 healthy controls were assessed by a comprehensive neurop.. Read More»
    DOI: 10.4172/2329-6895.10.12.527

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