Clinical Infectious Diseases: Open Access

Department of Molecular Biology and Medical Genetics, Kazakh National Medical University Named After S.D. Asfendiyarov, Almaty, Kazakhstan

Publications

• Case Report   
  Guillain-Barré Syndrome Following SARS-CoV-2 Pneumonia in a Patient Receiving Adjuvant Chemotherapy for Gastric Cancer: A Case Report
  Author(s): Bayan Nurgaliyeva*, Zhamal Otunbayeva, Olga Kan, Aizhan Moldakaryzova, Saken Khaidarov, Slu Izmailova and Abildayeva Gaukhar
  
  Guillain-Barré Syndrome (GBS) is an acute, progressive inflammatory polyneuropathy characterized by muscle weakness and distal sensory deficits. In the context of SARS-CoV-2 infection, GBS most commonly presents as a sensorimotor variant, frequently associated with facial paralysis and a demyelinating electrophysiological pattern. We report the case of a 47-year-old female diagnosed with stage IIb (T3, N1, M0) gastric adenocarcinoma who underwent gastrectomy followed by five cycles of adjuvant chemotherapy. During the fifth cycle, she developed SARS-CoV-2-associated pneumonia involving 30% of lung parenchyma and required hospitalization. Following recovery and discharge, the patient experienced progressive lower limb weakness and sensory disturbances. Electro Neuro Myo Graphy (ENMG) demonstrated mixed sensory and motor nerve involvement in both upper and lower extremities predo.. Read More»
  

  Abstract PDF