Epilepsy Journal

Professor, School of Medicine, Grififith University, Broad Beach, Queens land, Australia; and Profes, Chair Medical Law Sechenov Moscow First State University, Moscow, Russia

Publications

• Review Article   
  What is Epilepsy – when do we start treatment and with what?
  Author(s): Roy G Beran*
  
  Introduction: Epilepsy comprises ≥ 2 unprovoked seizures (>24 h apart), 1 unprovoked seizure with probability of recurrence (≥ 60%) or an epilepsy syndrome. What follows is consideration of treatment. Background: Newer ASMs offer adjunctive treatment but none has better efficacy than carbamazepine (CBZ) although possibly less adverse effects. Valproate (VPA) is preferred for generalised epilepsy (except child-bearing age women) with increased preference for the levetiracetam and lamotrigine (LTG). Despite decline for older ASMs, Beran supported CBZ. First unprovoked seizure has 30-50% chance of recurrence, rising to 70-80% with a second seizure. Percentages increase with abnormal neurologic examination, focal spikes on electroencephalography (EEG) and focal seizures. Most common epilepsy presentation to the emerg.. Read More»
  DOI: 10.37421/2472-0895.2021.7.141

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