Journal of Nursing & Care

ISSN: 2167-1168

Open Access

Robert L. Vender

Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, Penn State Health Milton S. Hershey Medical Center, 500 University Drive, HO 41, Hershey, PA 17033, USA

  • Commentary   
    Journey to the Center of a Disease: The Cystic Fibrosis Saga
    Author(s): Robert L. Vender* and Amanda Florey

    Since the first clinical description of the disease cystic fibrosis (CF) in 1938, there have been innumerable milestones in relation to delineation of disease pathogenesis and subsequent treatment which continue to this day. This narrative review: 1) details key discoveries that have significantly impacted overall CF patient health, 2) correlates these important advancements specifically to clinical observations from providers at the Penn State Health Milton S. Hershey Medical Center (PSH-HMC) adult CF program and 3) provides potential future directions since the regulatory approval of cystic fibrosis transmembrane conductance regulator (CFTR) protein therapies. With the availability of highly effective CFTR modulator therapies, providers from the PSH-HMC adult CF center have observed the following major changes in the health and lives of adult CF patients including: 1) improved survi.. Read More»
    DOI: 10.37421/2167-1168.2023.12.576

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Citations: 4230

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