Journal of AIDS & Clinical Research

ISSN: 2155-6113

Open Access

Ogugbue CJ

Department of Microbiology, Faculty of Science, University of Port Harcourt, P.M.B 5323, Choba, Rivers State, Nigeria

  • Research Article   
    Prevalent Hepatitis B Virus Genotypes Circulating among HIV Co-Infected Patients in an Urban City, South-South Nigeria
    Author(s): Ayodele MBO*, Ogugbue CJ, Frank-Peterside N and Tatfeng YM

    Hepatitis B Virus (HBV) has been classified into genotypes A-J which characteristically has different geographic origins, disease progression and responses to antiviral treatment. Co-infection caused by Human immunodeficiency virus (HIV) and HBV is common because they both share similar routes of transmission. In this study, we report the prevalent HBV genotypes circulating among HBV-HIV co-infected patients in Port Harcourt, south-south Nigeria. DNA was extracted from stored serum samples obtained from 25 HBV-HIV co-infected patients selected out of 535 HIV I/II sero-positive patients confirmed to be HBsAg positive from University of Port Harcourt Teaching Hospital (UPTH) and Obio Cottage Hospital both in Port Harcourt City. HBV genotyping was carried out using a nested Polymerase Chain Reaction (PCR) approach followed by Big-dye termination sequencing. The mega .. Read More»

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