Journal of Molecular Histology & Medical Physiology

ISSN: 2684-494X

Open Access

Lakshmi Bhai

Department of Pharmacy, Jawaharlal Nehru Technological University, Hyderabad, Telangana, India

  • Perspective   
    Multiple Kinds of Genetic Changes Can Lead to Cancer
    Author(s): Lakshmi Bhai*

    The proteins known as insulin-like growth factors (IGFs) share a lot of similarities with insulin in their sequence. IGFs are a component of a sophisticated system used by cells to interact with their physiologic environment. Two cell-surface receptors (IGF1R and IGF2R), two ligands (IGF-1 and IGF-2), a family of seven high-affinity IGF-binding proteins (IGFBP1 to IGFBP7), and associated IGFBP degrading enzymes, collectively known as proteases, make up this intricate system, which is frequently referred to as the IGF "axis." IGF-1 plays a role in controlling various aspects of brain development, such as neurogenesis, myelination, synaptogenesis, dendritic branching, and neuroprotection following neuronal damage. IGF-I serum levels that are greater in children have been linked to a higher IQ. IGF-1 regulates apoptosis, which influences how the cochlea deve.. Read More»
    DOI: 10.37421/2684-494X.2022.7.54

    Abstract HTML PDF

arrow_upward arrow_upward