Journal of Inflammatory Bowel Diseases & Disorders

ISSN: 2476-1958

Open Access

Jay Pravda

Department of Gastroentorology, Inflammatory Disease Research Centre, PO Box 32632 West Palm Beach, Florida, FL 33420, United States

  • Review Article   
    Pathophysiology and Treatment of Inflammatory Bowel Disease
    Author(s): Jay Pravda*

    Ongoing investigations have shown dysbiosis is related with fiery entrail illness (IBD). Notwithstanding, attempting to reestablish microbial variety through waste microbiota transplantation (FMT) or probiotic mediation neglects to accomplish clinical advantage in IBD patients. We played out a probiotic mediation on a recreated IBD murine model to explain their relationship. IBD was mimicked by the convention of Azoxymethane and Dextran Sodium Sulfate (AOM/DSS) to set up a colitis and colitis related neoplasm model on BALB/c mice. A solitary probiotic mediation utilizing Clostridium Butyricum Miyairi (CBM) on AOM/DSS mice to explain the job of probiotic in colitis, colitis related neoplasm, stomach microbiota, and safe cytokines was performed. We found dysbiosis happened in AOM/DSS mice. The CBM mediation on AOM/DSS mice neglected to further develop colitis and colitis related neoplas.. Read More»
    DOI: 10.37421/2476-1958.2022.7.172

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