Department of Pulmonology, University of Dammam, Dammam, Saudi Arabia
Commentary
Long Term Therapy with Lithium Interactions and Side Effects
Author(s): Hao Zhang*
Lithium is still the first choice for bipolar disorder prophylaxis, preventing manic and depressive episodes from returning. The longitudinal effects
of administering lithium far outweigh those of other mood stabilizers. The kidney, gastrointestinal, neurological, thyroid, metabolic, cognitive,
dermatological, cardiovascular and sexual side effects of lithium is all listed. Interstitial nephropathy is probably the most serious side effect of
lithium, usually seen after 10 to 20 years of use. Long-term lithium therapy also has beneficial side effects, such as anti-suicidal, antiviral and
anti-dementia effects. Long-term lithium treatment may be affected by pharmacokinetic and pharmacodynamics interactions, mostly with other
drugs. The narrative review of lithium-induced side effects and interactions that may affect its prophylactic effect in bipolar disorder is updated i.. Read More»
DOI:
10.37421/2472-1247.2023.9.252
Spanish 
Chinese 
Russian 
German 
French 
Japanese 
Portuguese 
Hindi 