Department of Government Analytical Laboratory, Ministry of Internal Affairs, Kampala, Uganda
Research Article
Allele Frequency Database for 21 Short Tandem Repeats in the Ugandan Population
Author(s): Jane Nabwowe*, Musa Kirya, Dianah Katiti, Tarsisius Byamugisha, Immaculate Natukwasa, Precious Nyangoma, Alex Nkusaule, Charles Kigozi, Francis Mbolwa, Amon Serunkuma, Agnes Namatovu and Kepher Kuchana Kateu
Genetic studies on the Ugandan population are very limited and little has been done to characterize its population structure. Here, we used 21 autosomal STRs included in the GlobalFilerTMAmplification Kit to amplify DNA from 1301 non-related adult individuals randomly selected from the four geographical regions of the country, namely Eastern, Western, Central and Northern region. The DNA samples were extracted using PrepFiler Express extraction protocol, amplified using the GlobalFilerTMPCR amplification kit and separated using capillary electrophoresis on the 3500xL Genetic Analyzer. A total of 342 alleles were observed ranging from 4 to 43.2 repeat units. Genotype distribution agreed with Hardy-Weinberg equilibrium (p > 0.05) except at D3S1358 loci that did not show significant departures from Hardy-Weinberg equilibrium after Bonferroni correlation. Tri-allelic patterns were observed a.. Read More»
DOI:
10.5281/zenodo.17706946
Journal of Forensic Research received 2328 citations as per Google Scholar report