Neurological Disorders

ISSN: 2329-6895

Open Access

Crystal Radinski

Department of Medicine, University of British Columbia, Canada

  • Research   
    Task-related Temporal Gamma EEG Coherence As A Marker Of Major Neurocognitive Disorder
    Author(s): Dina Rodinskaia*, Crystal Radinski and Jake Labuhn

    Background: Progressive deterioration of synaptic plasticity and synaptic connectivity between neurons is a neurophysiological hallmark of brain ageing and has been linked to the severity of dementia. We hypothesized that electroencephalographic evidence of the disruption of functional connectivity might be used to diagnose Alzheimer's dementia. Improving the accuracy and reducing the time needed to diagnose AD could allow timely interventions, treatments, and care cost reduction. In our previous study, we identified four promising markers. Temporal Gamma EEG coherence marker (TG_marker) was selected for evaluation. Methods: This blinded diagnostic test accuracy study examined diagnostic parameters for TG_marker in individuals with AD, vascular dementia, Parkinson's, depression and healthy controls. The TG_marker sensitivity, specifi.. Read More»
    DOI: 10.4172/2329-6895.10.9.513

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