Department of Medicine, University of British Columbia, Canada
 Research   
								
																Task-related Temporal Gamma EEG Coherence As A Marker Of Major Neurocognitive Disorder 
																Author(s): Dina Rodinskaia*, Crystal Radinski and Jake Labuhn             
								
																
						 Background: Progressive deterioration of synaptic plasticity and synaptic connectivity between neurons is a neurophysiological hallmark of brain ageing and has been linked to the severity of dementia. We hypothesized that electroencephalographic evidence of the disruption of functional connectivity might be used to diagnose Alzheimer's dementia. Improving the accuracy and reducing the time needed to diagnose AD could allow timely interventions, treatments, and care cost reduction. In our previous study, we identified four promising markers. Temporal Gamma EEG coherence marker (TG_marker) was selected for evaluation.
Methods: This blinded diagnostic test accuracy study examined diagnostic parameters for TG_marker in individuals with AD, vascular dementia, Parkinson's, depression and healthy controls. The TG_marker sensitivity, specifi.. Read More»
						  
																DOI:
								10.4172/2329-6895.10.9.513															  
Neurological Disorders received 1343 citations as per Google Scholar report