Department of Pharmacy, University of Baltimore, Baltimore, USA
Mini Review
Biological Mechanisms of Drug Resistance in Cancer Therapy
Author(s): Combrzyński Jacek*
Cancer remains one of the most challenging diseases to treat effectively, primarily due to the ability of cancer cells to develop resistance to
various therapeutic agents. Understanding the biological mechanisms underlying this drug resistance is crucial for developing more effective
treatments and improving patient outcomes. Drug resistance in cancer therapy can be classified into two broad categories: intrinsic resistance,
where cancer cells are inherently resistant to treatment and acquired resistance, where initially sensitive cancer cells develop resistance over
time. This article explores the key biological mechanisms contributing to drug resistance in cancer therapy. One of the primary mechanisms of
drug resistance in cancer is the alteration of drug targets. Many cancer therapies, particularly targeted therapies, are designed to interfere with
specific .. Read More»
DOI:
10.37421/2952-8100.2024.07.459
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