Journal of Morphology and Anatomy

ISSN: 2684-4265

Open Access

Capraru Oana Maria

University of Medicine and Pharmacy of Târgu Mureş, Târgu Mureș, Romania

  • Short Communication   
    The Role of Menin in the Thyroid Lesions
    Author(s): Capraru Oana Maria*

    Multiple Endocrine Neoplasia type 1 is a hereditary syndrome, with an autosomal dominant transmission, characterized by hyperplasia/ tumours in endocrine organs (parathyroids, pituitary, gastro-intestinal system). The gene involved is MEN1 gene on chromosome 11q13 which encodes menin, an oncosuppressive nuclear protein according to Knudson “two hit” hypothesis. Expression of menin and its inactivation in the thyroid gland have long been debated... Read More»
    DOI: 10.37421/2684-4265.2020.4.130

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