Journal of Morphology and Anatomy

ISSN: 2684-4265

Open Access

Article in Press

Volume 4, Issue 1 (2020)

    Research Article Pages: 1 - 7

    Immunohistochemical Expression of Cytokeratin 18 in Rat Sertoli Cells under Effect of Aluminium Hydroxide and Pomegranate Molasses

    Elsayed Mohammed Aly Metwally*, Meriam Ramzy Riad, Rasha Ibrahim Amer Ali, Wafaa Abdel Rahman Ahmed and Mona Abdel-Hameid Yehia

    DOI: 10.37421/JMA.2020.4.123

    Background: Sertoli cells are one of the major cell types in testes that provide nutrition and structural support for germ cell development. Cytokeratin 18 protein is consistently expressed in immature Sertoli cells of prepubertal seminiferous tubules, but is completely absent in normal, mature seminiferous tubules.

    Objective: The objective of this study was to examine the possible protective role of pomegranate molasses. Through immunohistochemical expression of cytokeratin 18 in the rat sertoli cells of prepubertal age after the administration of aluminum hydroxide.

    Materials and methods: Sixty male albino rats of prepubertal age were divided into three equal groups: (control group); (Aluminum hydroxide treated group) received oral aluminum hydroxide at a dose of 30 mg/kg b. wt/day; (protected group) received both aluminum hydroxide (at the same previous dose) and pomegranate molesses in a dose of 0.5 ml (PM) plus 0.5 ml distilled water orally. At the end of the experiment (8 weeks), all animals were sacrificed and their testes were excised. Paraffin sections were prepared for examing under the light microscope, used histomorphological stain and immunohistochemical DAB stain of Cytockeratin protein 18 by aviden biotin complex protocol.

    Results: After the administration of aluminum hydroxide (AD), some seminiferous tubules had disturbed basal lamina and disorganized germinal epithelium. The spermatogenic cells decreased in number with undifferentiated hyperprolifirating germ cells. The concomitant administration of pomegranate molasses with aluminum hydroxide showed alleviation in histopathological changes induced by aluminum hydroxide in the structures of testis. In addition, the increased number of sertoli cells was noticed in grouped treated with AD and decreased in group treated with concomitant administration of PM.

    Conclusion: The present study showed that exposure to aluminum hydroxide resulted in marked degenerative effects on the rats' testis, but they were improved with the concomitant administration of PM, as well as, the immunohistochemical detection of cytokeratin 18 in Sertoli cells may be provided a sensitive marker for immature or damaged testes.

    Research Article Pages: 1 - 7

    Anatomy of the Spine of an Elaphe Daguet (Cervus Elaphus)

    Dominique Pianel

    DOI: 10.37421/JMA.2020.4.124

    The growth of the branch in male elaphe deer (cervus elaphus) is a seasonal phenomenon resulting in a significant variation in the weight of the deer head of up to 14 kg.
    Comparative anatomy studies to identify which biomechanical structures are being implemented to adapt and cope with such predictable variations have been
    undertaken. The study of the angle of the spruce serouts of the tourniquet allowing a pulley return and a force vector was not conclusive; the complete dissection of the
    spine of a young male deer was undertaken. The results unequivocally demonstrated the obvious correlation between the weight of future antlers and the size of the
    diameter of the nuchal ligament in the daguet. Such results open the door to new questions about the correlation that might exist between the weight of the adornment,
    the presence of neuropeptide Y in the nuchal ligament and calcium production.

    Editor Note Pages: 1 - 1

    Morphology and Anatomy is the Collection of Innovations in the Research Field

    Abdelmonem Awad Hegazy

    DOI: 10.37421/JMA.2020.4.e125

    Journal of Morphology and Anatomy is a peer reviewed, open access journal that aims to understand human anatomy by analyzing its structure, function, development and evolution. The Journal also publishes original research articles on macroscopic anatomy, histological development, Morphological Sciences, Cell and Molecular Biology, Macroscopic Human Anatomy, and Microscopic Human Anatomy. Topics related to Macroscopic Animal Anatomy, Microscopic Animal Anatomy, History of Morphological Sciences, Morphology and Arts, Education in Morphology. It also publishes about the techniques for the Study of Morphology, Clinical Anatomy, Compared Anatomy, Pathological Anatomy, Anatomy and Anthropology, Embryology and Cell Biology. Morphology Applied to other Sciences like phonology, syntax, and semantics, the acquisition and processing of morphological information, mental lexicon, and morphological variation and change, models of morphology, morphological typology, the position of morphology in the architecture of the human language, and the evolution of language. The volume 3 includes the various aspects of morphology and anatomy has discussed by the authors from different parts of the world. In the research article, Mngu-Suur KR, et al. studied Morphometric Study the Male Reproductive Organs of the African Striped Ground Squirrel (Xerus erythropus) [1]. Iyiola S, et al. has discussed about the proliferation index of breast cancer among the Nigerian women is similar to other women from most parts of the world. The delay in presentation leads to high grades and advanced disease at presentation which eventually cause death [2]. Iyiola S et al. in their research article evaluated Mini Chromosomes Maintenance Complex Binding Protein as an Alternative Breast Cancer Cells Proliferative Marker to Monoclonal Ki67 [3]. Nnadozie O, et al. investigated Assessment of the Morphological Development of the Thymus in Turkey (Meleagris gallopavo) [4]. Abera M, et al. reviewed Maize Lethal Necrosis a Viral Disease, an Emerging Treat to Maize Production in Ethiopia in their review article [5]. Parés-Casanova PM has demonstrated in his research article about the results of this study raise future questions about the influence of skull biomechanics on its asymmetrical development, but also about how management, ingesta-specific properties (such as abrasiveness) and domestication can influence this response [6].

    Short Communication Pages: 1 - 5

    The Correlation between the frescos by Giorgio Vasari and Leonardo Da Vinci's Anatomy

    Grigol Keshelava

    DOI: 10.37421/JMA.2020.4.126

    The object of this research is the frescos of Giorgio Vasari. The details of each episode of the painting are interpreted in anatomical aspect and compared to the anatomical drawings of Leonardo da Vinci. The comparison reveals the similarity between the details of this painting and Leonardo’s anatomy.

    Short Communication Pages: 1 - 2

    New Approaches on High Fat Diet Research

    Cristian Sandoval*, Santibañez S

    DOI: 10.37421/JMA.2020.4.127

    Obesity is defined as an excess of body-fat mass. Reliable fat-mass quantitation requires sophisticated tools that are not widely available. BMI is a gross measurement of body fat where it could have an effect at the cellular level. Multiples researches have shown the effects of high-fat diet on behavioral eating patterns, body composition, lipid metabolism and insulin sensitivity, and the role of exercise on these parameters. Also, it is important to consider the positive effects of exercise on adipose tissue metabolism and to understand the mechanisms by which this tissue affects the kinetics of other macromolecules. Some intermittent energy restriction regimens have gained popularity as strategies for achieving weight loss and other metabolic health benefits. However, clinical studies comparing weight loss with intermittent energy restriction regimens to traditional continuous energy restriction in adults with overweight and obesity are limited. Although scientific evidence clearly shows the effects of high-fat diet on behavioral eating patterns, body composition, lipid metabolism and insulin sensitivity; it also important to characterize relationships between these parameters and the role of exercise and some intermittent energy restriction regimens, emphasizing the timing of dietary intake and other aspects of behavior that are linked to intake.

    Commentary Pages: 1 - 2

    Commentary on Ansa pancreatica: Review of the Literature

    Kympouris Sotirios

    DOI: 10.37421/ JMA.2020.4.128

    It has been almost 60 years since the ansa pancreatica was first described by Dawson and Langman in a rather innovative study based on radiographic evaluation of the intrapancreatic ductal configuration in cadaveric subjects. The proposed incidence, based on 120 subjects, was 21%. Undoubtedly a percentage high enough to raise an interest on this anatomic entity. But what does the ansa pancreatica represent?

arrow_upward arrow_upward