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Medicinal Chemistry

ISSN: 2161-0444

Open Access

Akash Marathakam

Department of Pharmaceutical Chemistry, National College of Pharmacy, Kerala, India

Publications
  • Review Article   
    Review on Anti−Cancer Potential of Novel Imidazothiazoles and their Synthetic Methods
    Author(s): Vajid Parasuraman Kunnath*, Shadiya Chediyan Kandy and Akash Marathakam

    In recent studies on cancer treatment, researchers find out that several enzymatic mutations lead to the development of cancerous cells. Such as Indoleamine 2,3-dioxygenase 1 (IDO1), B-Raf kinase, and ErB4 (HER4) kinase inhibitors. Imidazothiazole-based derivatives are gained more attention among scientists due to their wide variety of pharmacological activities, such as anti-fungal, anti-bacterial, anthelmintic, and anti-cancer activities as well as ease of synthesis of these compounds. During the search for compounds that can act as anti-neoplastic agents through inhibition of these enzymatic receptors, researchers found that imidazothiazole-based compounds and their derivatives show more potent anticancer activity. In this review, we focus on some traditional synthetic methods proposed by researchers to prepare imidazothiazole derivatives and their anticancer .. Read More»
    DOI: 10.37421/2161-0444.2023.13.674

    Abstract HTML PDF

Google Scholar citation report
Citations: 6627

Medicinal Chemistry received 6627 citations as per Google Scholar report

Medicinal Chemistry peer review process verified at publons

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