Department of Ear, Nose and Throat, Faculty of Medicine, Tanta University, Egypt
Research Article
The Utility of Remifentanil Compared with Nitroglycerin for Deliberate Hypotensive Anaesthesia throughout Tympanoplasty. Randomized and Observer-Blinded Clinical Trial
Author(s): Nagat S. EL-Shmaa*, Ashraf E Alzeftawy and Ahmed Younes
Background: The purpose of this randomized observer-blinded clinical trial was to evaluate the utility of
remifentanil compared with nitroglycerin for deliberate hypotensive anaesthesia throughout tympanoplasty.
Methods: Patients planned for elective typanoplasty under general anaesthesia were allocated to receive either
intravenous infusion of nitroglycerin 2-5 μg/kg/min (group NTG), or remifentanil 0.2-0.5 μg /kg/min (group REMI).
The primary outcome measures were to keep up MAP between 60 and 70 mmHg with ideal vision of operative site.
Results: Both studied agents induced deliberate hypotensive anaesthesia and achieved ideal vision of the
surgical site by decreasing bleeding, but optimum vision was provided at reasonable hypotension (MAP 70-75) in
group REMI however similar situation was.. Read More»
Journal of Clinical Anesthesiology: Open Access received 7 citations as per Google Scholar report
