Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, MB R3E 0J9, Canada
Mini Review
A Agricultural Pathogen Becomes a Delivery Vehicle for Vaccines
Author(s): Abdjeleel Emeterio*
The Vesicular Stomatitis Virus (VSV), a well-known livestock pathogen and prototypical non-segmented, negative-sense RNA virus, is a member
of the Vesiculovirus genus and the family Rhabdoviridae. Even though the virus is to blame for economically significant epidemics of vesicular
stomatitis in cattle, horses, and pigs, molecular biologists and virologists can still use VSV as a useful research tool. In fact, the development of
a reverse genetics approach for the recovery of infectious VSV from cDNA altered this virus's functionality and opened the door for its application
as a vaccine vector. Many other VSV-based vaccines have been developed, especially for high-consequence viruses. A highly effective VSVbased
vaccination against the Ebola virus just got clinical licensure. This review aims to give a comprehensive but succinct understanding of
.. Read More»
DOI:
10.37421/2684-4931.2022.6.126
Journal of Microbial Pathogenesis received 17 citations as per Google Scholar report
Spanish 
Chinese 
Russian 
German 
French 
Japanese 
Portuguese 
Hindi 