Journal of Tissue Science and Engineering

Tania Limongi

Publications

• Research Article
  Development, Characterization and Cell Cultural Response of 3D Biocompatible Micro-Patterned Poly-ε- Caprolactone Scaffolds Designed and Fabricated Integrating Lithography and Micromolding Fabrication Techniques.
  Author(s): Tania Limongi, Ermanno Miele, Victoria Shalabaeva, Rosanna La Rocca, Rossana Schipani, Natalia Malara, Francesco de Angelis, Andrea Giugni and Enzo di FabrizioTania Limongi, Ermanno Miele, Victoria Shalabaeva, Rosanna La Rocca, Rossana Schipani, Natalia Malara, Francesco de Angelis, Andrea Giugni and Enzo di Fabrizio
  
  Scaffold design and fabrication are very important subjects for biomaterial, tissue engineering and regenerative medicine research playing a unique role in tissue regeneration and repair. Among synthetic biomaterials Poly-ε- Caprolactone (PCL) is very attractive bioresorbable polyester due to its high permeability, biodegradability and capacity to be blended with other biopolymers. Thanks to its ability to naturally degrade in tissues, PCL has a great potential as a new material for implantable biomedical micro devices. This work focuses on the establishment of a micro fabrication process, by integrating lithography and micromolding fabrication techniques, for the realization of 3D microstructure PCL devices. Scaffold surface exhibits a combination in the patterned length scale; cylindrical pillars of 10 μm height and 10 μm diameter are arranged in a hex.. Read More»
  DOI: 10.4172/2157-7552.1000145

  Abstract PDF