Journal of Oncology Translational Research

ISSN: 2476-2261

Open Access

Sylvain Baruchel

Department of Pediatrics and Research Institute, The Hospital for Sick Children,
555 University Avenue, Toronto, Ontario M5G 1X8

  • Review Article
    Advances in ALK Targeted Therapy for Neuroblastoma
    Author(s): Libo Zhang and Sylvain BaruchelLibo Zhang and Sylvain Baruchel

    Significant advances have been made to understand the association between ALK genetic aberrations and disease prognosis in neuroblastoma. ALK targeted therapies are evolving quickly and several randomized controlled trials of ALK inhibitors are underway or nearing completion in adult cancers. Ongoing research will bring new challenges and newer technologies to fully define the pathogenic and prognostic alterations, to stratify the risk of recurrence or progression, and to develop optimal monitoring and treatment strategies in this malignancy... Read More»
    DOI: 10.4172/2476-2261.1000114

    Abstract PDF

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