Journal of Pharmacognosy & Natural Products

Sunday P Bako

Publications

• Research Article
  Toxicity Effects of Methanolic Extract of Euphorbia hirta-Honey Mixture in Albino Rats
  Author(s): Ifeanyi Peter Onyeka, Mohammed M Suleiman and Sunday P BakoIfeanyi Peter Onyeka, Mohammed M Suleiman and Sunday P Bako
  
  The Igbo people of the South-eastern part of Nigeria claims that a combination of Ehirta and honey has therapeutic effect for Ulcer. The study was designed to scientifically evaluate the phytochemical composition of E. hirta and the safety of the phytomedicine. Nine hundred gram (900 g) of E. hirta gave an average yield of 49.05 g of the extract and this gave percentage yield of 5.45% when extracted with continuous extraction process of Soxhlet apparatus. Phytochemical screenings of E. hirta showed that the extract contains alkaloids, Tannins, Saponins, Glycosides, Flavonoids and Unsaturated steroids. Acute toxicity studies showed that LD50 was greater than 5000 mg/kg. The phytomedicine of E. hirta combined with did not produce significant changes in the blood biochemical and haematological parameters. Though slight reductions were witnessed in bloo.. Read More»
  DOI: 10.4172/2472-0992.1000147

  Abstract PDF