Journal of Bioanalysis & Biomedicine

Shweta Dubey

Publications

• Review Article
  Releasing the Brakes in Cancer
  Author(s): Shweta Dubey and Ankita GargShweta Dubey and Ankita Garg
  
  Cancer is a heterogeneous group of diseases where abnormal cell growth with potential to invade other body parts takes control of normal homeostasis and becomes fatal if not timely and rightly treated. There are more than 100 types of cancers characterized so far and many yet to be identified. World Health Organization estimates, that worldwide in 2012 there were 4 million new cancer cases and 8.2 million cancer related deaths. Amongst various treatment options available for cancer, immunotherapy offers an approach where the focus is on enhancing or even inducing an antitumor immune response. Induction or enhancement of anti-tumor immune response is a formidable challenge in cancer because tumor cells use multiple immune evasion strategies and avoid being detected or eliminated by immune cells. Immune checkpoints refer to a network of stimulatory or inhibitory signaling pathways in th.. Read More»
  DOI: 10.4172/1948-593X.1000147

  Abstract PDF