Genotypic Analysis of the Virulence and Antibiotic Resistance Genes in Campylobacter species in silico.
Author(s): Nusrat Nahar and Ridwan Bin RashidNusrat Nahar and Ridwan Bin Rashid
Campylobacter species is responsible for 400-500 million diarrhea cases worldwide every year. Emergence of antibiotic resistance has further complicated the scenario. A wide range of virulence factors and resistance genes are present in Campylobacter species and it is hypothesized there are genotypic variations in the prevalence of these genes. The study was conducted to investigate the presence of virulence and antibiotic resistance genes as well as to investigate difference in prevalence rate based on genotype through in silico tools. Among 26 species studied, sixteen isolates (61.54%) had the cdtB gene that breaks the double helix bonds. The cdtA genes were detected in ten (38.46%) C. jejuni strains while fifty percent (n=13) isolates harbored the cdtC genes. Ten isolates that harboured all three adjacent cdt g.. Read More»
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