South Africa						                            
                            
						
 Research Article
												Vulval Tuberculosis: The Histomorphological Spectrum in Patients with
HIV Co-Infection and AIDS 						
Author(s): Nhlonzi GB, Ramdial PK, Nargan K, Lumamba KD, Pillay B, Kuppusamy JB, Naidoo T and Steyn AJCNhlonzi GB, Ramdial PK, Nargan K, Lumamba KD, Pillay B, Kuppusamy JB, Naidoo T and Steyn AJC             
						
												
				 Objective: Vulval tuberculosis (TB) is reported rarely. The histomorphological spectrum and diagnostic mimicry thereof in patients with concomitant HIV infection/ AIDS is unreported to date. This study aimed to appraise the histopathologic spectrum of vulval TB in HIV co-infected patients and to identify histopathological diagnostic challenges, mimicry and pitfalls.  Methods: Ten year retrospective study that reappraised the histomorphological features of vulval TB in HIV-infected patients.  Results: The clinical descriptions of the biopsied lesions from 19 patients that form the study cohort encompassed nodules (9), ulcers (5), hypertrophy/edema (3) and abscesses (2). The main microscopic features included necrotizing and non-necrotizing granulomatous inflammation, ulceration with a zoned inflammatory response and chronic suppurative inflammation. The necrotizing component had the ty.. Read More»
				  
												DOI:
												 10.4172/2155-6113.1000719 
																	  
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