Pulmonary & Respiratory Medicine

Murali G Krishna

Publications

• Case Report
  Amiodarone Pulmonary Toxicity: A Case Report and Review of the Literature
  Author(s): Zaineb Shamim, Pooja R Sarkar and Murali G KrishnaZaineb Shamim, Pooja R Sarkar and Murali G Krishna
  
  Amiodarone, a common and efficacious antiarrhythmic agent, carries with it an array of serious side effects, most notably, amiodarone induced pulmonary toxicity, or APT. Patients typically present with dyspnea, and chest X-rays will show interstitial infiltrates. In severe cases, toxicity can lead to fibrosis and even respiratory failure. In this report, such effects are demonstrated based on the case of an 85 year old female who presented with multiple hospital admissions for multilobar pulmonary infiltrates and acute hypoxic respiratory failure, which did not respond to antibiotic therapy. She had, at the time of admission, been on amiodarone for over 2 years. The patient’s amiodarone was discontinued, and she was started on prednisone. The patient displayed a significant clinical and radiographic improvement within 4 weeks. I.. Read More»
  DOI: 10.4172/2161-105X.1000343

  Abstract PDF