Journal of Nephrology & Therapeutics

Komolafe OO

Publications

• Research Article
  Microalbuminuria in a Cohort of Ambulatory HIV-Positive Nigerians
  Author(s): Komolafe OO, Aderibigbe A, Olanrewaju TO, Chijioke A, Salami AK and Rafiu MOKomolafe OO, Aderibigbe A, Olanrewaju TO, Chijioke A, Salami AK and Rafiu MO
  
  Quantification of urine albumin is an established method of screening, diagnosis and monitoring the progression of kidney disease. Renal disease is a frequent accompaniment of Human Immunodeficiency Virus (HIV) infection. Limited data exists with regard to the epidemiology of microalbuminuria in indigenous African HIV patients. To study this issue further, we evaluated 90 antiretroviral-naïve HIV seropositive adults and compared them with an equivalent number of age and sex matched HIV seronegative controls. Individuals with known confounders of urine albumin were excluded from the study. We found microalbuminuria in 35.6% of HIV cases as against 13.3% in the seronegative group (p=0.001). In addition, there was a positive correlation between cluster of differentiation 4 (CD4) cell count and microalbuminuria (p=0.001). Similarly, decreasing estimated g.. Read More»
  DOI: 10.4172/2161-0959.1000179

  Abstract PDF