Journal of AIDS & Clinical Research

Jose Saban

Publications

• Research Article
  Hyper-inflammation and Endothelial Activation in HIV Infected Patients with Detectable and Undetectable Viral Load
  Author(s): Enrique Bernal, Jose Saban, Angeles Munoz, Irene Marin, Ana Garcia-Medina, Tomas Vicente and Alfredo CanoEnrique Bernal, Jose Saban, Angeles Munoz, Irene Marin, Ana Garcia-Medina, Tomas Vicente and Alfredo Cano
  
  Although HIV and antiretroviral therapy (ART) have been linked with an increased cardiovascular risk, the pathological pathways remain unknown. We assessed whether secretory phospholipase A2 (sPLA2), high-sensitivity C-reactive protein (hs-CRP), vascular cell adhesion molecule (VCAM), thiobarbituric acid reactive species (TBARS), Superoxide dismutases (SOD), adiponectin and resistin were elevated in HIV infected patients with detectable and undetectable viral load compared to a control group matched for age, sex and cardiovascular risk factors. We evaluated its correlation with traditional and no traditional cardiovascular risk factors and carotid intima-media thickness. Levels of sPLA2 (median [IQR]) were 8.35 (5.36, 9.6) pg/ml, hsCRP were 3.3 (IQR, 1.27, 5.28) mg/L, VCAM 945.6 (I.. Read More»
  DOI: 10.4172/2155-6113.1000164

  Abstract PDF