Journal of Biometrics & Biostatistics

Jianrong Wu

Biography

 Jianrong Wu working in Department of Biostatistics and Computational Biology
University of Rochester Medical Center
Rochester, New York 14642, USA

Research Interest

My primary research interest is to develop new methodology for designing clinical trial and pre-clinical study. Pediatric cancer clinical trial is often conducted as a single-arm phase II trial or a randomized phase III trial with time-to-event endpoint, particular with a proportion of patients cured. Statistical methodology for such trial design is relatively scarce. My research is to provide more flexible and powerful statistical design for such trials. For pediatric pre-clinical tumor xenograft model, my research interest is to develop new methodology to assess the anti-tumor activity of the treatment for single drug testing and to assess the synergism for drug-drug combination testing. My other methodology research interests are survival data analysis, randomized phase III survival trial design and group sequential trial design and likelihood-based small sample and large sample inference.