Journal of AIDS & Clinical Research

Jean-Paul Viard

Publications

• Research Article
  Structural and Functional Arterial Parameters, Immunovirological Control and Vitamin D in HIV-Infected Patients
  Author(s): Alexandra Yannoutsos, Davide Agnoletti, Julie Peroz-Froz, Camille LY, Helene Lelong, Jirar Topouchian, Jacques Gilquin, Segolene Boucly, Hafeda Rostane, Michel E Safar, Jean-Paul Viard and Jacques BlacherAlexandra Yannoutsos, Davide Agnoletti, Julie Peroz-Froz, Camille LY, Helene Lelong, Jirar Topouchian, Jacques Gilquin, Segolene Boucly, Hafeda Rostane, Michel E Safar, Jean-Paul Viard and Jacques Blacher
  
  Objective: HIV-infected patients still experience higher Cardiovascular (CV) mortality rates, even if an adequate viral suppression is achieved. In addition, vitamin D insufficiency, a common condition in HIV-infected patients, is increasingly associated with CV risk. We therefore aim to investigate relationships between immunological parameters, antiretroviral therapy, plasma vitamin D and arterial parameters, including aortic stiffness and wave reflections, in HIV-infected patients who achieved viral suppression but possibly remain at increased CV risk. Methods: We conducted a cross-sectional study including 178 middle-aged HIV-infected patients. HIV infection was controlled in a large number of participants, representative of a real-world setting. In addition to carotid Intima Media Thickness (IMT), central hemodynamic parameters involved aortic Pulse Wave Velocity (PWV), carotid A.. Read More»
  DOI: 10.4172/2155-6113.1000375

  Abstract PDF