National Liver Institute,
Shiben Elkom
Egypt
Research Article
Gastrointestinal Stromal Tumors: Diagnostic and Therapeutic Challenges
Author(s): Ibrahim Abdelkader Salama, Waleed Hammam Mosa, Mohamed Elsherbini, Mohamed Abbasy, Mohamed Houseni and Mohamed BadrIbrahim Abdelkader Salama, Waleed Hammam Mosa, Mohamed Elsherbini, Mohamed Abbasy, Mohamed Houseni and Mohamed Badr
Background: Gastrointestinal stromal tumors (GIST) are the most common mesenchymal neoplasms of the digestive system. They originate from the interstitial cells of Cajal and are characterized by the over expression of KIT protein (Tyrosine Kinase), and they pose a diagnostic and therapeutic dilemma.
Objective: A challenge in diagnosis and treatment of GIST
Patients & Methods: This is a retrospective study of GIST cases that diagnosed and treated in our center during the past 5 years. These studies include clinical characteristics, imaging techniques, neoadjuvant therapy, surgical techniques, immunohistochemistry, and prognosis of such cases. Results: Sixteen patients were diagnosed as having GIST (12 males/4 females) with a mean.. Read More»
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