Journal of Nephrology & Therapeutics

Ebru Yilmaz

Publications

• Research Article
  Urine Matrix Metalloproteinase-3 Level as a Biomarker for Monitoring in Familial Mediterranean Fever Attacks
  Author(s): Betul Sozeri, Ebru Yilmaz, Nida Dincel, Gozde Gozuoglu, Kadriye Ozdemir, Ipek Kaplan Bulut, Hasan Gun Z and Sevgi MirBetul Sozeri, Ebru Yilmaz, Nida Dincel, Gozde Gozuoglu, Kadriye Ozdemir, Ipek Kaplan Bulut, Hasan Gun Z and Sevgi Mir
  
  Objective: Matrix metalloproteinase-3 (MMP-3) has been implicated in experimental and clinical models of human inflammatory conditions. Increased MMPs levels have been shown in serum and body fluids in inflammatory conditions. Familial Mediterranean Fever (FMF) is an inherited, auto inflammatory disease characterized by recurrent self-limited bouts of fever and localized inflammation. We aimed to investigate whether urine MMP-3 level can serve as a biomarker for monitoring attack in FMF patients in daily practice. Methods: We studied 50 patients diagnosed with FMF according to Tel Hashomer criteria and 32 age-matched healthy controls. We determined all subjects both in attack (FMF-AP) and attack free period (FMF-AFP) groups. Serum and urine samples were obtained within the first 6-24 h of the AP, and 10 days later after the attack (AFP). The serum samples were measured on the same day.. Read More»
  DOI: 10.4172/2161-0959.1000164

  Abstract PDF