Journal of Computer Science & Systems Biology

Daming Wei

Publications

• Research Article
  Fractal-Dimension-Based Method for Quantification of T-Wave Alternans Using Short Time Series
  Author(s): Motoki Sakai and Daming WeiMotoki Sakai and Daming Wei
  
  The presence of T-Wave Alternans (TWA) in an electrocardiogram (ECG) has been certified as an important predictor for the risk of sudden cardiac death (SCD). TWA is a beat-to-beat change in the amplitude of a T-wave, but is rarely visible to the naked eye. Thus, automatic detection and quantification of TWA are desirable. While several automatic algorithms, such as the periodogram method or the modified moving average method (MMA), have been developed to detect or quantify TWA, most conventional methods do not effectively measure short-duration TWA (SDTWA) (<16 beats). In this paper, we proposed a fractal dimension based SDTWA quantification method, and evaluated it with simulated ECG signals with SDTWA episodes (<16 beats) based on the European ST-T database. In the evaluation, the proposed method was applied to ECG signals with TWA amplitude of 5, .. Read More»
  DOI: 10.4172/jcsb.1000108

  Abstract PDF