Medicinal Chemistry

Arunesh K Dixit

Publications

• Research Article
  Indian Herb Hemidesmus indicus - A Potential Source of New Antimicrobial Compounds
  Author(s): Zafar Mehmood, Arunesh K Dixit, Ajay Singh, S Farooq and Suman Lata ChhimwalZafar Mehmood, Arunesh K Dixit, Ajay Singh, S Farooq and Suman Lata Chhimwal
  
  The results of present study support the view that Hemidesmus indicus and its isolated bioactive compound (2H4MB) showing potential antibacterial and antifungal activities that could be utilized to control infectious diseases caused by the test pathogens and Candida albicans in the human system. Analysis of essential oil from root of the plant obtained by using Clevenger apparatus by hydro distillation was undertaken through GC-MS. 2-Hydroxy- 4-methoxybenzaldehyde (2H4MB) was the major chemical entity (99.41%) amongst 10 identified compounds. The in vitro antibacterial activity of 3 different extracts (Hexane, Methanol and Aqueous) and Bioactive compound 2-Hydroxy-4-methoxybenzaldehyde (2H4MB) as well as MIC values of isolated compound (2H4MB) were performed. The most active extract was found to be the hexane extract showing the maximum zone of inhibition of 22 mm against Staphylococc.. Read More»
  DOI: 10.4172/2161-0444.1000422

  Abstract PDF