Journal of Nephrology & Therapeutics

Ana Carolina Alves de Andrade Silva

Publications

• Research Article
  Functional and Morphostructural Evaluation of the Kidneys of Wistar Rats after the Use of a Protein-Based Food Supplement
  Author(s): Andressa Alves de Andrade Silva, Antônio Gonçalves Rodrigues Junior, Avelar Alves da Silva and Ana Carolina Alves de Andrade SilvaAndressa Alves de Andrade Silva, Antônio Gonçalves Rodrigues Junior, Avelar Alves da Silva and Ana Carolina Alves de Andrade Silva
  
  Introduction: Athletes are increasingly using whey protein–based dietary supplements that, used improperly, may create health risks. Objective: To evaluate changes in glomerular filtration, renal tubular function, and histopathological alterations associated with the use of protein-rich food supplements on the kidneys of Wistar rats. Method: Twelve Wistar rats were divided into control (Group I) and intervention (Group II) groups. Group II received the supplement for 14 fourteen days. Urine samples were collected from the animals for urinalysis and blood samples were collected for the determination of urea, creatinine, sodium, potassium, and chloride levels. At the end of the experiment, the animals were euthanized and the kidneys were collected for a histopathological study. Results: After the supplementation, reduced urea levels (p=0.00930) and increased urinary density (p=0.. Read More»
  DOI: 10.4172/2161-0959.1000270

  Abstract PDF