Journal of Nephrology & Therapeutics

Ahmed Alsaloom

Publications

• Research Article
  Efficacy of Cinacalcet for the Treatment of Secondary Hyperparathyroidism in CKD Patients on Peritoneal or Hemo Dialysis: The Middle-East Experience
  Author(s): Abdullah Al-Hwiesh, Ahmed Alsaloom, Krishan Lal Gupta, Ibrahiem Saee, Raja Ramchandran and Fahad Al-MohannaAbdullah Al-Hwiesh, Ahmed Alsaloom, Krishan Lal Gupta, Ibrahiem Saee, Raja Ramchandran and Fahad Al-Mohanna
  
  Background:Management of secondary hyperparathyroidism is challenging with traditional therapy. The calcimimetic cinacalcet hydrochloride acts on the calcium-sensing receptors to increase its sensitivity to calcium, thereby reducing parathyroid hormone (PTH) secretion. Calcimimetics lower parathyroid hormone levels without increasing calcium and phosphorus levels. Aim:To evaluate effectiveness of cinacalcet hydrochloride in reducing serum intact PTH levels in patients with end stage renal diseases and secondary hyperparathyroidism. Material methods: The study included patients who were receiving regular dialysis and had inadequately controlled secondary hyperparathyroidism despite standard treatment (calcium based phosphorus binders and/or sevlamer carbonate at .. Read More»
  DOI: 10.4172/2161-0959.1000113

  Abstract PDF