Fats are the body's most concentrated source of energy (37 kJ/g). They also help to absorb fat-soluble vitamins such as A, D, E, and K, as well as other fat-soluble biologically active components. Because they are soluble in organic solvents and are absorbed and transported in a way comparable to fats, vitamins A, D, E, and K are known as fat-soluble vitamins. Vision, bone health, immunological function, and coagulation are just a few of the physiological processes that fat-soluble vitamins play a part in. The biochemistry, transport, and functions of these vitamins are discussed in this review, with a focus on deficient disorders and potential toxicities.They absorb in the lymph, are transported in the circulation via carrier proteins, and can be stored in the liver and fatty tissues since they are fat soluble.