Journal of Biomedical and Pharmaceutical Sciences

Arboviruses, or arthropod-borne viruses, represent a significant global public health concern due to their ability to cause widespread human infections. These viruses are primarily transmitted to humans through the bites of infected mosquitoes, making these vectors essential players in the arbovirus transmission cycle. Mosquitoes have developed an intricate immune system to combat invading pathogens, including arboviruses. Research in recent years has shed light on how the mosquito's systemic immune response plays a crucial role in the detection and control of arboviral infections. Understanding this process can provide valuable insights into developing innovative strategies for controlling arboviral diseases. This article explores the mechanisms behind how arboviruses are detected through the mosquito's systemic immune response and its implications for public health.

Cancer is a complex and devastating disease that continues to be a global health challenge. Despite significant advancements in cancer research and treatment modalities, traditional therapies often suffer from limited efficacy and severe side effects. Nanomedicine has emerged as a promising approach to revolutionize cancer treatment by utilizing nanoscale materials to deliver therapeutic agents with high precision and efficacy. This article explores the current state of cancer nanomedicine, novel methods employed in the field, and the medical opportunities it presents for improving cancer management. Cancer remains one of the leading causes of mortality worldwide. Conventional cancer treatments, such as chemotherapy, radiation therapy, and surgery, have shown some success but are often associated with severe side effects due to their non-selective nature.

The field of medicinal chemistry plays a vital role in the discovery and development of new drugs and therapeutic agents. However, traditional drug development approaches often rely on the extensive use of synthetic chemicals, leading to adverse environmental impacts and potential harm to ecosystems. In response to growing concerns about ecological sustainability, researchers and pharmaceutical industries have started exploring innovative methods for designing and synthesizing ecologically friendly medicinal materials. This review aims to provide an in-depth analysis of the current state of research in this emerging area and highlights novel approaches that offer promising alternatives to conventional drug design and synthesis. Medicinal chemistry is a multidisciplinary field that involves the design, synthesis, and evaluation of bioactive compounds with potential therapeutic properties.

Frontotemporal Dementia (FTD) is a devastating neurodegenerative disorder characterized by progressive deterioration of behavior, language, and executive functions. As one of the most common forms of early-onset dementia, FTD poses significant challenges to affected individuals, their families, and society at large. This paper presents an evaluation assessment of "Where Is Us Now" in Frontotemporal Dementia, aiming to explore the current state of knowledge, research, and management strategies surrounding this complex condition. Through a comprehensive analysis of existing literature, clinical studies, and emerging therapies, this assessment seeks to shed light on the progress made in understanding FTD and its impact on individuals and their communities.