Chemical Sciences Journal

Finding the data that is most relevant to a given context is a major obstacle to reusing and integrating existing data. The scientific literature that provides descriptions of the experiments that led to the data is the primary source of metadata. We manually annotated 100 recent open access publications in Analytical Chemistry as semantic graphs to encourage the development of natural language processing techniques for extracting this data from articles. Because we are particularly interested in the subject, which also falls under the purview of a number of ontologies and controlled vocabularies, we concentrated our efforts on articles that included a mention of mass spectrometry in their experimental sections. The resulting gold standard dataset is accessible to the general public and can be used to verify automated methods for locating this metadata in the literature. We also made a few observations regarding the experiment structure, description, and open access publication in this journal.

Food protein conversion into functional biomaterials, including their application for loading and delivering physiologically active pharmaceuticals and nutraceuticals, has received increased attention over the past ten years. Since proteins are biocompatible, amphipathic, and readily available, they outperform other platforms for the creation of nanodelivery systems. Additionally, the encapsulation and release properties of proteins can be altered by modifying specific functional groups and unique molecular structures. Preparing protein nanoformulations has required a variety of physical and chemical approaches, each based on distinct protein chemistry. From the perspective of their preparation, functionality, stability, and physiological behavior, the chemistry of the reorganization and/or modification of proteins into functional nanostructures for delivery is the primary focus of this review.

Clinical biochemistry is a field that primarily relies on biochemical analyses of various body fluids, the most important of which are urine, blood, and cerebrospinal fluid. Centuries of scientific advancements have paved the way for the relatively recent significant advancements in this field. Standard analytical chemistry in the clinical setting has seen decades of significant advancements thanks to technological innovation and the introduction of cutting-edge instruments. Clinical biochemistry was founded on primitive methods like Richard Bright's (1789-1858) test for proteinuria in cases of suspected renal disease, in which a candle flame heated a tablespoon of urine. The beginning of the twentieth century could only be traced to minor technological advancements. In 1920, "a centrifuge, a urinometer, two monocular microscopes, two small substage microscope lights, a Bunsen burner, a Dubosq colorimeter, a basal metabolic rate machine, an electro-cardiograph, a microtome, a knife, a paraffin bath, a few antisera and an assortment of test tubes, beakers, and pipettes" were among the items in the clinical pathology laboratory.

In addition to providing a variety of pleasures of taste, diet provides energy and nutrition necessary for survival. Numerous studies have demonstrated that the main nutrients in a diet, like protein, carbohydrates, and fat, play a significant role in controlling aging and longevity. It is a very interesting question to see if other ingredients in food can help prevent aging and increase longevity. Based on recent research, we talked about plant ingredients that can control metabolism, target TRP channels, mitophagy, senescence pathways, and circadian rhythms, and increase longevity. The development of new intervention tools for the prevention of aging and diseases related to aging would benefit from a deeper comprehension of the specific effects and mechanisms of dietary ingredients on longevity regulation.

From synthesis to materials and applications, this thematic issue covers a wide range of current polymer chemistry topics. The use of click photochemistry in the synthesis of polymers and organic molecules, as well as the combination of polymers and supramolecular chemistry for the assembly of polymer fibers and the production of well-defined polysaccharides, are examples of synthetic methods. Cryogels, reinforced hydrogels, and 3D-printed poly(caprolactone) biomaterials are among the materials discussed. This thematic issue also discusses the properties of thermoresponsive and self-healing materials. Finally, the synthesis of drug carriers made possible by polymerization-induced self-assembly is discussed. The issue also demonstrates the multidisciplinary nature of polymer science, as evidenced by the use of supramolecular motifs, organic coupling reactions, and photocatalysis in the creation of new polymer materials for specific applications.