Reports in Thyroid Research

Thyroid and Pregnancy: Association of lipid profile with Thyroid function test in Thyroid disorder patients

Abstract

Sujit Kumar Jha

HypoThyroidism is that the most typical reason behind secondary dyslipidemia. it’s thus necessary to assess Thyroid operate take a look at before beginning hypolipidemic medication. The gland disease is additional susceptible to have vessel and associated issues. These risk factors square measure cumbersome to regulate if not detected earlier and manifested later with severe clinical constellations. Our study assesses the frequency and spectrum of dyslipidemia in varied styles of thyroid sickness within the population residing in south western a part of Asian nation. Methods: this can be a cross sectional study dispensed in suspected Thyroid disorder patients (n=276) and classified as euThyroidism (n=55), subclinical gland disease (n=89), primary gland disease (n=122) and first thyrotoxicosis (n=10) patients and to ascertain the association with lipide profiles
within the Department of organic chemistry, Universal school of Medical Sciences Teaching Hospital, Bhairahawa Asian nation. blood serum fT3/fT4 and hormone estimations were dispensed by competitive assay technique and sandwich double protein assay technique severally victimization commercially provided reagents (Human, Germany). the factors for dyslipidemia were obtained by National steroid alcohol Education professional Panel/Adult Treatment Protocol III (NCEP/ATPIII). Results: Out of all cases, dyslipidemia was largely related to primary gland disease (55.07%) followed by subclinical gland disease (38.04%) than euThyroid (5.79%) and first thyrotoxicosis (3.62%) severally. Out of all cases, the spectrum of dyslipidemia was largely determined for slashed lipoprotein (18.5%) followed by enlarged TG (10.1%). Moreover, it considerably disagree in relevancy lipoprotein (p=0.009) and TG/HDL (p=0.02) wherever as non vital as compared to alternative lipide profile in numerous teams. Conclusions: Our study discovered the shut association of thyroid sickness with dyslipidemia with enlarged TG, low lipoprotein and enlarged TG/HDL. The enlarged TG/HDL and/or non-HDL/HDL may be higher indicator than single lipide abnormality, that must be observed prospectively in massive population.