Awoke Seyoum Tegegne*, Godada Keleb, Molalign Tarekegn Minwagaw, Haile Mekonnen, Denekew Bitew Belay, Abay Kassa Tekile, Lijalem Melie, Eyerus Asmare and Muluwork Ayele
Background: One of the sub-Sahran African countries with high number of people living with HIV is Ethiopia. Among the regions in Ethiopia, Amhara region is the one in which many people are under HIV medication treatment. This research has been conducted with objective to detect variable significantly affected the level of adherence under cART in Government Hospitals throughout Amhara region.
Methods: A cohort secondary data found from a random sample of 1540 HIV-positives under cART were used for current investigation. A binary logistic regression modeling was conducted in data analysis. The study was conducted in 18 government hospitals in Amhara region, Ethiopia.
Results: The predictors like patients’ age (AOR=1.020, 95% CI: 1.001, 1.1200), baseline CD4 cell count (0.980, 95% CI: 0.764, 0.991), visits of health institutions (AOR=0.9900, 95% CI: 0.6723, 0.9990), patients living without their partner (AOR=1.01, 95% CI: 1.003, 1.112), male patients (AOR=1.01, 95% CI: 1.001, 1.021), patients living in urban area (AOR=0.98, 95% CI: 0.96, 0.99), educated patients (AOR=0.950, 95% CI: 0.92, 0.98), socially violated patients (AOR=1.012, 95% CI: 1.008, 1.234), opportunistic adult patients (AOR=1.062, 95% CI: 1.049, 1.191), patients who did not disclosed their disease (AOR=1.062, 95%CI: 1.038, 1.254) had significant effect on non-adherence to medication. Similarly, WHO stages significantly affected on the variable of interest.
Conclusions: Socio-demographic variables such as age, baseline CD4 cell count, patients living without their partners, male patients, rural patients, patients faced social violence, opportunistic adult patients, patients who did not disclosed their disease status need espetial attion. Health related education is recommended for non-adherent patients to be adherent for the prescribed treatment.
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